Ruminants Immune System

• Research demonstrates this cost in 24 hrs could be as much as the following depending on the acuteness of challenge:

Based on acute clinical infection

• The hidden challenges to building resilience to challenge are many and include:
  • Environmental, physical, and psychological stressors
    • Comfort and movement, heat/cold, feed and water availability, transportation, overcrowding, noise, etc.
  • Poor feed hygiene
    • Increasing exposure to pathogens and mycotoxins
  • Sub-optimal rumen function
    • Reduced digestibility and absorption
    • Increased inflammation and wasting nutrients.
  • Intestinal permeability
    • Low nutrient absorption
    • Leaky gut

• Stress is one of the major limiting factors to optimizing the genetic production potential of your herd or flock.
• Chronic (Prolonged) stress leads to prolonged elevated levels of circulating Cortisol which has been shown to suppress the immune system and have negative influence on reproduction.
• Acute and Chronic stress has also been shown to contribute to increased intestinal permeability.
• Chronic Stress and disease (both clinical and subclinical) and leaky gut cause:
  • Activation of the animal’s immune system
  • Inflammation and tissue damage, which alters function.
  • Partitioning of nutrients to favour the control of infection and tissue repair in place of tissue accretion.
  • Priority to shift from production/growth to survival.
  • Long-term negative effects on production and reproduction
• Minimise the animal’s exposure to known environmental, physical and psychological stressors where possible.
• Minimise diseases (clinical and subclinical)
• Focus efforts on the three pillars to create a more resilient herd or flock with better production outcomes:
  • Optimal Rumen Function
  • Pathogen Control, and
  • Hindgut health and Integrity

Pathogen Control	Optimal Rumen Function	Hindgut Health
CELMANAX SCP CALSPORIN GUSTOR NRGY MICRO-AID	CELMANAX SCP INTELLIBOND TRACE MINERALS LIPIDOL ULTRA LITHONUTRI CALSPORIN GUSTOR NRGY MICRO-AID TOXO XL	CELMANAX SCP INTELLIBOND TRACE MINERALS LIPIDOL ULTRA CALSPORIN GUSTOR NRGY BETAIN 96 MICRO-AID TOXO XL

* References available on request

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